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API’s & Intermediates of Interest
Active Pharmaceutical Ingredients of Interest
CARIPRAZINE
Chemical Name
N’-[trans-4-[2-[4-(2,3-Dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-N,N-dimethylurea
CAS Number
839712-12-8
Therap. Category
Antipsychotic
Molecular Formula
C
2
1
H
3
2
Cl
2
N
4
O
Molecular Weight
427.41
BREXPIPRAZOLE
Chemical Name
7-[4-[4-(1-benzothiophen-4-yl)piperazin-1-yl]butoxy]quinolin-2(1H)-one
CAS Number
913611-97-9
Therap. Category
Antiphychotic
Molecular Formula
C
2
5
H
2
7
N
3
O
2
S
Molecular Weight
433.57
CABERGOLINE
Chemical Name
1-[(6-Allylergolin-8-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea
CAS Number
81409-90-7
Therap. Category
To treat Hyperprolactinemia
Molecular Formula
C
26
H
37
N
5
O
2
Molecular Weight
451.615
EMPAGLIFLOZIN
Chemical Name
(1S)-1,5-anhydro-1-(4-chloro-3-{4-[(3S)-tetrahydrofuran-3-yloxy]benzyl}phenyl)-D-glucitol
CAS Number
864070-44-0
Therap. Category
Antidiabetic
Molecular Formaula
C
23
H
27
ClO
7
Molecular Weight
450.91
LINAGLIPTIN
Chemical Name
8-[(3R)-3-aminopiperidin-1-yl]-7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione
CAS Number
668270-12-0
Therap. Category
Antidiabetic
Molecular Formula
C
25
H
28
N
8
O
2
Molecular Weight
472.553
VILDAGLIPTIN
Chemical Name
(2S)-1-[2-[(3-hydroxy-1-adamantyl)
amino]acetyl]pyrrolidine-2-carbonitrile
CAS Number
274901-16-5
Therap. Category
Antidiabetic
Molecular Formula
C
17
H
25
N
3
O
2
Molecular Weight
303.406
TENELIGLIPTIN
Chemical Name
{(2S,4S)-4-[4-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)-1-
piperazinyl]-2-pyrrolidinyl}(1,3-thiazolidin-3-
yl)methanone
CAS Number
760937-92-6
Therap. Category
Antidiabetic
Molecular Formula
C
22
H
30
N
6
OS
Molecular Weight
426.58
MIRABEGRON
Chemical Name
2-(2-Amino-1,3-thiazol-4-yl)-N-[4-(2-{[(2R)-2-hydroxy-2-phenylethyl]amino}ethyl)
phenyl]acetamidephenyl]acetamide
CAS Number
223673-61-8
Therap. Category
To treat Overactive bladder
Molecular Formula
C
2
1
H
2
4
N
4
O
2
S
Molecular Weight
396.51
VORTIOXETINE
Chemical Name
1-{2-[(2,4-Dimethylphenyl)sulfanyl]
phenyl}piperazine
CAS Number
508233-74-7
Therap. Category
Antidepressant
Molecular Formula
C
18
H
22
N
2
S
Molecular Weight
298.45
TAVABOROLE
Chemical Name
5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole
CAS Number
174671-46-6
Therap. Category
Antifungal
Molecular Formula
C
7
H
6
BFO
2
Molecular Weight
151.93
OXCARBAZEPINE
Chemical Name
10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide
CAS Number
28721-07-5
Therap. Category
Anticonvulsant
Molecular Formula
C
1
5
H
1
2
N
2
O
2
Molecular Weight
252.268
ESLICARBAZEPINE
Chemical Name
(9S)-9-hydroxy-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaene-2-carboxamide
CAS Number
236395-14-5
Therap. Category
Anticonvulsant
Molecular Formula
C
1
7
H
1
6
N
2
O
3
Molecular Weight
296.326
CLOMIPRAMINE
Chemical Name
( 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamine
CAS Number
303-49-1
Therap. Category
Antidepressant
Molecular Formula
C
1
9
H
2
3
ClN
2
Molecular Weight
314.852
RIMEGEPANT
Chemical Name
[(5S,6S,9R)-5-Amino-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl] 4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxylate
CAS Number
1289023-67-1
Therap. Category
Antimigraine
Molecular Formula
C
28
H
28
F
2
N
6
O
3
Molecular Weight
534.568
ATOGEPANT
Chemical Name
(3S,5S,6R)-3-amino-6-methyl-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)piperidin-2-one.
CAS Number
1374248-81-3
Therap. Category
Antimigraine
Molecular Formula
C
29
H
23
F
6
N
5
O
3
Molecular Weight
603.528
SODIUM NITROPRUSSIDE
Chemical Name
Disodium pentacyanonitrosylferrate(2-) dihydrate
CAS Number
13755-38-9
Therap. Category
To lower blood pressure
Molecular Formula
C
5
FeN
6
Na
2
O
Molecular Weight
261.921
ACTIVE PHARMACEUTICAL INTERMEDIATES OF INTEREST
Chemical Name
2-(Chloromethyl)-4-methylquinazoline
CAS Number
109113-72-6
Therap. Category
Intermediate for Linagliptin
Molecular Formula
C
1
0
H
9
ClN
2
Molecular Weight
Intermediate for Linagliptin
Chemical Name
1-(3-methyl-1-phenyl-1H-pyrazol-4-yl)piperazine
CAS Number
401566-79-8
Therap. Category
Intermediate for Teneligliptin
Molecular Formula
C₁₄H₁₈N₄
Molecular Weight
242.32
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